This paper explores how the notion of mutuality can be an ethical driver for engaging participation in the co-design of future health practices and spaces. The context is the design and delivery of a co-design workshop to understand the future practices and ideal spaces for a University health education and research precinct. Were port on how mutuality was employed as a framework across four distinct parts of an online co-design workshop. First, to develop the participatory toolkit; second, to engage the interdisciplinary facilitation team; third, to engage participants in envisioning future practices to take place in the precinct; and finally, to link the translation of future practices and values to spatial principles to drive architectural planning processes. Through the experience, mutuality was identified as encapsulating the most important qualities in the emerging and future health practices in the precinct. As a value set, it provided a way to shift the aspirations for the building and programs into the future and towards what is shared and mutually beneficial to the stakeholders, the immediate and wider community, and the environment.